IndraLab

Statements

JAK2 phosphorylates JAK2 on Y221. 7 / 7
2 2 | 3
rlimsp
"Other sites of autophosphorylation in Jak2 include Tyr221 and Tyr570 [52]."
15575979
signor
"Autophosphorylation of jak2 on tyrosines 221 and 570 regulates its activity with phosphorylation of tyrosine 221 increasing kinase activity"
15143187
signor
"JAK2 is autophosphorylated on tyrosines 221 and 1007. tyrosines 221 and 570 in JAK2 may serve as regulatory sites in JAK2, with phosphorylation of tyrosine 221 increasing kinase activity and phosphorylation of tyrosine 570 decreasing kinase activity"
15143187
rlimsp
"In this study, mass spectrometry and two-dimensional peptide mapping were used to determine that tyrosines 221, 570, and 1007 in JAK2 are autophosphorylated."
15143187
hprd
No evidence text available
15143187
rlimsp
"Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity."
15143187
hprd
No evidence text available
15143188