IndraLab

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APC inhibits USP22. 2 / 2

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"In contrast, the APC and CDC20 E3 ligase complex negatively regulates USP22 activity by targeting it for degradation, presumably allowing CCNB1 downregulation so that cells can exit mitosis and enter anaphase."

27030811

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"Therefore, APC and CDC20 E3 ligase complex promotes USP22 protein degradation, presumably allowing CCNB1 degradation for cells to exit M phase."

27030811

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IndraLab

Statements

APC inhibits USP22. 2 / 2

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