IndraLab

Statements


USP36 deubiquitinates POLR1A. 1 / 1
1 |

"?In particular, we discovered that the largest subunit of RNA polymerase I (RNAPI) is stabilized via Ubp10-mediated deubiquitination.|USP36, the human ortholog of Ubp10, complements the ubp10螖 allele for RNAPI stability, pre-rRNA processing, and cell growth in yeast, suggesting that deubiquitination of RNAPI may be conserved in eukaryotes."