IndraLab

Statements

VCL activates KCNMA1. 4 / 4
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"Even in this study, BK channel activation led to a shift of the zero-current potential by -25 mV."
19096717
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"The S272V mutation caused a shift in BK channel V 1/2 to the depolarizing direction by 45 mV (V 1/2 = 67 +/- 2 mV) relative to that modulated by the wild-type gamma1 subunit (XREF_FIG and XREF_TABLE)."
27022192
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"Instead, the activation of L-type Ca 2+ channels by BayK 8644 caused a dramatic increase in BK channel activity and a shift of the reversal potential of the ARPE-19 cells by -22.6 mV."
19096717
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"In 11.1 mM glucose, the non peptidyl BK channel blocker paxilline increased the height of beta-cell action potentials (APs) by 21 mV without affecting burst- or silent-period durations."
20643769