IndraLab

Statements

CALM inhibits KCNQ1. 4 / 4
| 1 2 1
reach
"Moreover, overexpression of CaM reduced current amplitudes of KCNQ2, KCNQ4, and KCNQ5, but not those of KCNQ1 and KCNQ3."
23087646
reach
"Coexpression of CaM in Chinese hamster ovary (CHO) cells strongly reduced currents of KCNQ2, KCNQ4, and KCNQ5, but not KCNQ1 or KCNQ3."
15901836
sparser
"The slowly activating potassium current IKs was shown to be increased by elevation of Ca i , as due to a relief of KCNQ1 inactivation by calmodulin in a Ca 2+ dependent way (Ghosh et al., xref )."
24098284
eidos
"Phosphatidylinositol 4,5 - bisphosphate ( PIP2 ) and Ca 2 + - calmodulin prevented Kv7.1 inactivation triggered by Ca 2 + - free external solutions , where Ser 182 at the S2-S3 linker relays the calmodulin signal from its inner boundary to the external pore to allow proper channel conduction ."
33355140