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AKT1 phosphorylates TSC2 on T1462. 1 / 6
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reach
"RT results in high activation of protein kinase B (PKB), which is responsible for the phosphorylation of TSC2 at the Thr1462 site, resulting in TSC2 inactivation and consequently promoting mammalian target of rapamycin complex 1 (mTOR) activation [39]."