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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

FANCI activates BRCC3. 1 / 1

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"Our global proteomics experiment also revealed several commonly downregulated key DNA repair proteins ( Figure 5C ) such as ( i ) POLD1 which synthesizes DNA during repair ,26 ( ii ) USP47 which facilitates base-excision repair ,27 ( iii ) FANCI which mediates the repair of DNA double strand breaks and interstrand crosslinks ,28 and ( iv ) BRCC3 which stabilizes the accumulation of BRCA1 at DNA breaks ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...