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Statements


OTUD1 inhibits function OTUD1. 1 / 1
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eidos
"OTUD1 ( Ovarian Tumor Family Deubiquitinase 1 , FDR = 3.74 x 10-13 ) can inhibit nuclear translocation and transcriptional activity of the IFNgamma-activated transcription factor IRF3 ( Lu et al ., 2018 ) , and loss of function of OTUD1 is associated with auto-immune diseases mediated by interferons ( Lu et al ., 2018 ) ."