IndraLab

Statements

USP1 binds EcR-B1. 6 / 6
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reach
"Increased levels of 20E antagonizes phosphorylation of Akt and instead promotes 20E responsive gene transcription indirectly by promoting phosphorylation of USP1, which enhances EcR-B1 and USP1 binding to ecdysone response elements."
31955616
reach
"The presence of EcR-A, however, reduced the binding of EcR-B1 and USP-1 by about 50%."
15282165
reach
"Activation of a delayed-early gene encoding MHR3 by the ecdysone receptor heterodimer EcR-B1 and USP-1 but not by EcR-B1-USP-2."
10373539
reach
"The EcRE1 at -342 was necessary but not sufficient for the activational response but was the only one of the three putative EcREs to bind the EcR-B1 and USP-1 complex in gel mobility shift assays and was responsible for the silencing action of EcR-B1-USP-1 in the absence of hormone."
10373539
reach
"The EcR-B1 and USP-1 heterodimer was shown to bind to EcRE-1, and this binding was prevented by the addition of excess USP-2."
15455050
reach
"EcR-B1 and USP-1 heterodimer complex, E74B, E75B and BR-C Z2 transcription factors were first responsive genes to the ecdysone in mature cells and these genes are probably responsible for preparation of PCD process in mature midgut cells."
27620558