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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Phosphorylated AKT leads to the phosphorylation of NOS3 on serine. 2 / 2

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"102 Leptin induces Akt phosphorylation 103 and phosphorylated Akt then induces phosphorylation of the eNOS serine residue, which heightens its activity."

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"Akt phosphorylation is known to induce eNOS (Ser ) phosphorylation (Fulton, 2016), and was previously described by our research group as an important stimulus for maintaining basal NO production (Van Langen et al., 2012)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...