IndraLab

Statements

Glyburide inhibits PYCARD. 3 / 3
| 3
reach
"As displayed in Fig. 3b, ASC monomers (22 kDa) and higher order oligomers in cross-linked cytosolic pellets were attenuated by CLAN transfection or glyburide treatment."
30291237
reach
"Consistently, glibenclamide also blocked the oligomerization of ASC (XREF_FIG) and the association of NLRP3 and ASC (XREF_FIG and XREF_SUPPLEMENTARY) in mouse BMDMs in response to 25-HC treatment."
27779191
reach
"In agreement with the effects seen previously on IL-1beta secretion and caspase-1 activation glyburide and parthenolide did not inhibit AIM2 dependent ASC oligomerisation."
22216309