IndraLab

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USP7 deubiquitinates IRS-1/2. 4 / 4
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"These results clearly indicate that the rapid dissociation of USP7 from IRS-1/2 in response to insulin and IGF-I stimulation may enable the subsequent ubiquitination and proteasomal degradation of IRS[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
22634009
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"We hypothesized that USP7 deubiquitinates IRS-1/2 and prevents their proteasomal degradation."
22634009
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"Furthermore, we have recently reported that a deubiquitinase, USP7 deubiquitinates IRS-1/2, resulting in their stabilization [XREF_BIBR]."
30338032
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"Based on our results, USP7 deubiquitinated IRS-1/2 resulting in increase in their stabilization."
22634009