IndraLab

Statements

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"Still, it is reasonable to assume that our model of SLO in AGMs produced an initial severe inflammatory response that was followed by some form of minor lymphatic reorganization.Although the inflammat[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"First, CD4 effectors recognize cognate Ag in the SLO which together with inflammation from infection, induces their trafficking to the lung."
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"Overall, the presence of SLO or SLS results in an increased inflammation signature early in the infection timeline, while SLS promotes a sustained inflammatory response 48 hours post-infection."
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"Furthermore, intradermal injection of the toxins results in pronounced skin inflammation, which either resolves quickly within a few h (SLO induced inflammation) or presents a chronic process with ongoing inflammation for weeks (alpha-toxin)."
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"The results showed that DMY could significantly relieve vascular hyporesponsiveness caused by LPS and this effect could be blocked by MaxiK and K inhibitors incubation previous to NE treatment, which suggests that DMY may inhibit the inflammatory response, thus reverse the over-excited MaxiK and K channels in VSMCs.Accumulating evidence shows that the activity of ion channels, especially the potassium channel on ASMCs, plays a pivotal role in affecting the contractile state of the peripheral arteries."
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