IndraLab

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"However, neither exchange of the conserved glutamic acid to alanine (YOD1 E96A) nor even more profound mutations of the putative TRAF6 binding motif abolished YOD1 association (XREF_FIG and XREF_FIG), indicating that binding of TRAF6 MATH to YOD1 UBX domain is not mediated through a typical TIM."