IndraLab

Statements

EGF leads to the phosphorylation of STAT3 on Y705. 10 / 15
3 | 2 8 2
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"Furthermore, DDIAS knockdown suppressed EGF-induced STAT3 Y705 phosphorylation (Fig. xref ) and inhibited the nuclear translocation of IL-6–mediated pSTAT3 (Fig. xref )."
31900385
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"Alantolactone, a sesquiterpene lactone derived from Inula helenium , has been found to interact with the STAT3 SH2 domain at Arg595 and inhibit IL-6- or EGF-induced STAT3 phosphorylation at Tyr705, th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
35868477
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"There is evidence showing that STAT3 activation is dependent on Ca2+ signal in breast cancer cells, and phosphorylation of STAT3 at Tyr705 by EGF can be substantially inhibited upon intracellular Ca2+ chelation [ xref ]."
32517717
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"Specifically, constitutive and epidermal growth factor-induced phosphorylation of STAT3 on Y705 was observed only in SCC but not in either immortalized (HaCaT) or normal keratinocyte strains."
15173005
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"EGF treatment induced a biphasic STAT3 phosphorylation at Y705 in miR-204 overexpressing cells in the first hours, whereas pY705-STAT3 was barely detectable in control cells."
27457246
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"In addition, neither HIV + exosomes nor EGF induced the phosphorylation of STAT3 at Y705 ( xref , xref ), although these cells displayed basal levels of phosphorylation of STAT3 ( xref )."
32051269
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"KDI1 does not block EGFR’s RTK activity directly but interferes with EGF-induced phosphorylation of Tyr-705 in STAT3 protein [ xref ]."
24743778
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"Because EGF has been reported to activate STAT3 via phosphorylation on tyrosine in EGFR-overexpressing cells [36,37] , we attempted to determine whether the application of EGF treatment to the DU145 c[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21497499
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"Similar to what was observed in the piceatannol-treated cells, EGF-induced phosphorylations on both the Tyr705 and Ser727 of STAT3 were significantly reduced in the cells treated with neutralizing IL-[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21497499
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"EGF-induced phosphorylation of Stat3 at tyrosine 705 and Stat3-dependent transactivation were also impaired."
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