IndraLab

Statements

EGF leads to the phosphorylation of STAT3 on Y705. 15 / 15
3 | 2 8 2
sparser
"Furthermore, DDIAS knockdown suppressed EGF-induced STAT3 Y705 phosphorylation (Fig. xref ) and inhibited the nuclear translocation of IL-6–mediated pSTAT3 (Fig. xref )."
31900385
sparser
"Alantolactone, a sesquiterpene lactone derived from Inula helenium , has been found to interact with the STAT3 SH2 domain at Arg595 and inhibit IL-6- or EGF-induced STAT3 phosphorylation at Tyr705, th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
35868477
sparser
"There is evidence showing that STAT3 activation is dependent on Ca2+ signal in breast cancer cells, and phosphorylation of STAT3 at Tyr705 by EGF can be substantially inhibited upon intracellular Ca2+ chelation [ xref ]."
32517717
sparser
"Specifically, constitutive and epidermal growth factor-induced phosphorylation of STAT3 on Y705 was observed only in SCC but not in either immortalized (HaCaT) or normal keratinocyte strains."
15173005
bel
"To address this problem, we use quantitative mass spectrometry to analyze dynamic effects of HER2 overexpression on phosphotyrosine signaling in human mammary epithelial cells stimulated by epidermal growth factor (EGF) or heregulin (HRG). [This is from the 'Suplementary Table with Full Data Set\" (http://www.nature.com/msb/journal/v2/n1/suppinfo/msb4100094_S1.html). The cutoff used was a 2.5 fold or greater increase at any of the 5, 10 or 30 minute time points.]"
17016520
reach
"EGF treatment induced a biphasic STAT3 phosphorylation at Y705 in miR-204 overexpressing cells in the first hours, whereas pY705-STAT3 was barely detectable in control cells."
27457246
bel
"EGF-induced phosphorylation of the tyrosine residues 845, 1068, and 1148 as well as the phosphorylation of tyrosine 317 of p46 Shc. EGF-induced phosphorylation of Stat3 at tyrosine 705"
12842895
rlimsp
"In addition, neither HIV+ exosomes nor EGF induced the phosphorylation of STAT3 at Y705 (61, 62), although these cells displayed basal levels of phosphorylation of STAT3 (Fig. 7B)."
32051269
sparser
"In addition, neither HIV + exosomes nor EGF induced the phosphorylation of STAT3 at Y705 ( xref , xref ), although these cells displayed basal levels of phosphorylation of STAT3 ( xref )."
32051269
sparser
"KDI1 does not block EGFR’s RTK activity directly but interferes with EGF-induced phosphorylation of Tyr-705 in STAT3 protein [ xref ]."
24743778
reach
"Because EGF has been reported to activate STAT3 via phosphorylation on tyrosine in EGFR-overexpressing cells [36,37] , we attempted to determine whether the application of EGF treatment to the DU145 c[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21497499
rlimsp
"However, STAT3 phosphorylation (Tyr705) by EGF was substantially inhibited with intracellular calcium chelation (Fig. 5J–L)."
23686305
bel
"To address this problem, we use quantitative mass spectrometry to analyze dynamic effects of HER2 overexpression on phosphotyrosine signaling in human mammary epithelial cells stimulated by epidermal growth factor (EGF) or heregulin (HRG). [This is from the 'Suplementary Table with Full Data Set\" (http://www.nature.com/msb/journal/v2/n1/suppinfo/msb4100094_S1.html). The cutoff used was a 2.5 fold or greater increase at any of the 5, 10 or 30 minute time points.]"
17016520
sparser
"Similar to what was observed in the piceatannol-treated cells, EGF-induced phosphorylations on both the Tyr705 and Ser727 of STAT3 were significantly reduced in the cells treated with neutralizing IL-[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21497499
sparser
"EGF-induced phosphorylation of Stat3 at tyrosine 705 and Stat3-dependent transactivation were also impaired."
12842895