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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SOS1 binds CAV1 and GRB2. 1 / 1

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"In order to determine whether phospho-caveolin-1 expression sustains RAS signaling, we introduced in to HCT116-Cav-1 AS cells either a full-length caveolin-1 expression construct (WT) or a mutant form of caveolin-1 that is deficient in tyrosine phophorylation at residue 14 (Caveolin-1 Y14F) and assayed for the association of caveolin-1 with the two signaling molecules Grb2 and SOS1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...