IndraLab

Statements

PSMD14 deubiquitinates SF3B4. 3 / 3
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"Moreover, PSMD14 played a carcinogenic role by deubiquitinating SF3B4, promoting protein stabilization of SF3B4 and then mediating alternative splicing regulation of HNRNPC/SF3B4 complex through m A modification pathway."
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"Whether HNRNPC and SF3B4 can both be deubiquitinated by PSMD14 could be further studied."
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"As expected, PSMD14 notably reduced SF3B4 ubiquitination (Fig. 4B), while SF3B4 ubiquitination was elevated after PSMD14 down-regulated (Fig. 4C)."
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