IndraLab

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KCNG1 inhibits replication. 3 / 3
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"Role of the NF-κB pathway in the inhibition of lytic replication by K13."
17957251
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"To confirm the above results and to examine the role of the NF-κB pathway in the K13-induced inhibition of lytic replication, we generated stable clones of BCBL1-TREx-RTA cells expressing Flag-tagged wild-type K13 (i.e. without fusion with ER TAM ) and its two NF-κB-defective mutants, K13-58AAA and K13-67AAA, respectively xref ."
17957251
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"To rule out the possibility that the inhibition of lytic replication by K13 in the previous studies was an artifact of K13 over-expression, we examined whether silencing of endogenous K13 expression by RNA interference will induce lytic gene expression in PEL cells."
17957251