IndraLab

Statements


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reach
"As POH1 is a deubiquitinating enzyme responsible for substrate deubiquitination during proteasomal degradation, we determined whether POH1 binds to p53 or Bim and induces ubiquitination and proteasomal degradation."

sparser
"We determined the interaction between POH1 and p53 (or Bim) in QGY-7701 cells by co-IP ( xref )."

sparser
"However, the specific interaction between POH1 and p53 (or Bim) needs to be further validated."

sparser
"We studied the interaction between POH1 and p53 (or Bim) in QGY-7701 cells by co-immunoprecipitation ( xref ) and examined if POH1 affected the half-life of p53 and Bim using CHX (protein synthesis inhibitor)."

reach
"We studied the interaction between POH1 and p53 (or Bim) in QGY-7701 cells by co-immunoprecipitation and examined if POH1 affected the half-life of p53 and Bim using CHX (protein synthesis inhibitor)."

reach
"These results suggest that POH1 may interact with p53 or Bim."

reach
"We determined the interaction between POH1 and p53 (or Bim) in QGY-7701 cells by co-IP."