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PKC phosphorylates USP1. 2 / 2
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"Here, we report that the insect steroid hormone 20-hydroxyecdysone (20E) regulates calcium influx via phospholipase Cgamma1 (PLCG1) to modulate the protein kinase C phosphorylation of the transcription factor ultraspiracle (USP1) in the lepidopteran insect Helicoverpa armigera."
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"These results suggest that 20E activates PLCG1 via the ErGPCR and Src family kinases to regulate Ca (2+) influx and PKC phosphorylation of USP1 to subsequently modulate gene transcription for metamorphosis."
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