IndraLab

Statements


Cyclin phosphorylates USP1. 2 / 2
| 2

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"Specifically, we demonstrate that USP1 is phosphorylated in mitosis by cyclin dependent kinases (Cdks), and that this phosphorylation event may prevent premature degradation of USP1 during normal cell cycle progression."

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"During mitosis, phosphorylation of Usp1 by cyclin dependent kinases partially protects it against degradation via the APC/C Cdh1 Ub ligase."