IndraLab

Statements

HBX19818 inhibits USP10. 3 / 3
| 1 2
reach
"Notably, P22077, HBX19818, and HBX19818 analogs including Compounds 3, 7, and 9 also inhibit USP10 in mutant-FLT3-expressing cells."
35627217
reach
"However, a recent study (Weisberg et al., 2017) revealed that P22077 and HBX19818 may also inhibit the deubiquitinase activity of USP10 and induce the proliferation inhibition of mutant-FLT3 (FLT3-ITD)-positive cancer cells."
30319415
eidos
"Along with USP7 , P22077 and HBX19818 has also been reported to inhibit USP10 , promoting degradation of FLT3-mutant AML cells [ 174 ] ."
32354135