IndraLab

Statements

LY294002 inhibits COPS5. 3 / 3
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reach
"Our results also demonstrate that the AKT signaling pathway is involved in the regulation of Jab1 by Bcr-Abl because the AKT inhibitor LY294002 but not the ERK inhibitor PD98059 reduces Jab1 promoter activity and mRNA expression."
21935931
reach
"These results demonstrated that the PI3K inhibitor LY294002 could reduce Jab1 and beta-catenin but promote BRSK1 expression; BRSK1 expression might be at least associated with the PI3K and Akt pathway[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
25036402
reach
"Besides, PI3K and Akt may participate in the regulation of Jab1 and COPS5 by Bcr-Abl since PI3K and Akt inhibitor LY294002 decreases the promoter activity and mRNA level of Jab1 and COPS5."
29535627