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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EGF binds EGFR, INS, and INSR. 2 / 2

| 2

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sparser

"Scatchard analysis of the binding of EGFR and IR with EGF and insulin, respectively, yields concave-up or curvilinear plots that indicate the presence of two classes of binding sites."

24758840

➶

sparser

"Negative cooperativity was also observed both in EGFR-EGF and IR-insulin interactions, suggesting that the underlying mechanisms of activation of these receptors by ligand binding may be similar."

24758840

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...