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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified USP17L2 leads to the ubiquitination of Snail1. 2 / 2

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"The function of Dub3 is likely conserved from Drosophila to mammals, and knockdown of Dub3 increases, whereas Dub3 expression decreases, the ubiquitination and degradation of Snail1."

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"In agreement with this observation, expression of beta-TRCP1 and FBXL14 increased Snail1 polyubiquitination (XREF_FIG), which was attenuated by expression of WT-Dub3 (lanes 3 versus 2, lanes 6 versus 5, XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...