IndraLab

Statements


| 4

sparser
"Importantly, USP14 IRIF formation was significantly ( P < 0.0002) diminished in shATG7-expressing cells pretreated with the USP14 inhibitor IU1 before IR treatment (Figure xref and  xref ), suggesting that the catalytic activity of USP14 was needed for its recruitment to DSB sites."

sparser
"AKT, which mediates Ser432-USP14 phosphorylation, was required for IRIF formation by USP14."

sparser
"We first examined whether AKT regulates IRIF formation by USP14."

sparser
"Autophagy inhibition leads to increased USP14 IRIF formation."