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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53 is methylated on R333. 3 / 3

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"The methylation of p53 at arginine 333, 335 and 337 by PRMT5 was independently validated and shown to suppress p53-mediated target gene expression and apoptosis ( xref )."

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"The type II protein arginine transferase, PRMT5, interacts with and methylates p53 at R333, R335 and R337 following DNA damage [ xref ]."

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"In particular, PRMT5 interacts with and methylates p53 at R333, R335 and R337 upon DNA damage ( xref )."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

TP53 is methylated on R333. 3 / 3

Our Sources:

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