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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 inhibits hydrolase. 1 / 1

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"During chronic hepatitis C virus (HCV) infection (green), ISG15 appeared to have a proviral role86,87 because its overexpression reduced the responsiveness of the cell to interferon-α (IFNα) by maintaining the abundance of Ubl carboxy-terminal hydrolase 18 (USP18), a negative regulator of type I interferon receptor signalling89."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...