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USP18 inhibits hydrolase. 1 / 1

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"During chronic hepatitis C virus (HCV) infection (green), ISG15 appeared to have a proviral role86,87 because its overexpression reduced the responsiveness of the cell to interferon-α (IFNα) by maintaining the abundance of Ubl carboxy-terminal hydrolase 18 (USP18), a negative regulator of type I interferon receptor signalling89."

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USP18 inhibits hydrolase. 1 / 1

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