IndraLab

Statements

Modified PEX5L increases the amount of HCN1. 3 / 3
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"In the retina, loss of TRIP8b decreases the amount of HCN1 that is expressed, but the channel still traffics to the surface of retinal neurons (unpublished data)."
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"We had previously been surprised to find that loss of TRIP8b did not decrease the surface expression of HCN1 in the retina (beyond that dictated by the reduction in total HCN1 protein available) as it does in cortical neurons [XREF_BIBR]."
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"The loss of TRIP8b also reduces the expression of HCN1 in the retina, which may result in visual features carrying less information regarding the animal 's velocity 50."
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