IndraLab

Statements


METTL14 increases the amount of UCHL5. 4 / 4
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"As shown in Fig. 4 J–K, METTL14 silencing significantly suppressed UCHL5 expression in VSMCs, whereas this trend was reversed by YTHDF1 overexpression."

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"In summary, METTL14 increased UCHL5 m 6 A level and promoted UCHL5 expression in AS by recruiting YTHDF1.NLRP3 inflammasome is a key risking factor promoting AS progression [ 10 ]."

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"Therefore, we came to the conclusion that METTL14 increased UCHL5 m 6 A level and promoted UCHL5 expression by recruiting YTHDF1, thereby enhancing VSMC proliferation, migration and phenotype switchin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Collectively, UCHL5 upregulation accelerated VSMC proliferation, migration, inflammation and phenotypic switching during AS progression by activating NLRP3 inflammasome.Taken together, our research re[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"