IndraLab

Statements


2 | 2

reach
"Recruitment of CYLD, HOIP and Sharpin to TNF-RSC in response to TNFalpha was not affected in RIPK1 S321A (A/A) MEFs."

No evidence text available

No evidence text available

reach
"Interestingly, after caspase mediated cleavage during apoptosis, the N-terminal fragment of HOIP also binds to the DUBs OTULIN and CYLD, which are down-regulators of LUBAC mediated ubiquitination, providing a further regulatory feedback loop."