IndraLab

Statements

COPS5 decreases the amount of RAD51. 3 / 3
| 3
reach
"Furthermore, Jab1 depletion not only decreased the level of Rad51 but also affected its activity, as indicated by loss of Rad51 causing extensive chromosomal breaks, leading to apoptosis."
22797071
reach
"These results suggest that depletion of Jab1 and CSN5 reduces the expression of Rad51, leading to reduce ability of NPC cells to repair DNA lesions."
22867945
reach
"These results suggest that Jab1 depletion reduces the expression of Rad51, leading to a reduction in the ability of cells to repair DNA lesions and an increase in apoptosis, thus sensitizing NPC cells to cisplatin, IR and UV."
22797071