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Ribose inhibits IFIH1. 1 / 1

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"Therefore, the ribose 2′‐O‐methyl group on the first nucleotide marks viral RNA as “self” which prevents the activation of the RNA sensors Mda5, TLR7, and RIG‐I, as well as avoids recognition of RNA by the interferon‐induced translation inhibitors, IFIT1 and IFIT2 (Figure 2)."

31694072

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Ribose inhibits IFIH1. 1 / 1

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