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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SIRT1 binds KCNMA1. 1 / 1

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"To further investigate the BK channel α subunits as potential targets of SIRT1, we found that SIRT1 interacted with BK channel α subunits but not the β2 or β4 subunits, and the α subunit acetylation levels were modulated by inhibition of SIRT1 activity in hippocampus slices, suggesting direct acetylation of the BK channel α subunit by SIRT1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...