IndraLab

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USP9X leads to the deubiquitination of BCL10. 2 / 2

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"Mechanistically, USP9X interacts with Bcl10 of the Carma1-Bcl10-Malt1 (CBM) complex and removes the TCR-induced ubiquitin chain from Bcl10, which facilitates the association of Carma1 with Bcl0-Malt1."

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reach

"Finally, the ubiquitin specific protease 9X (USP9X) interacts with BCL10 in activated T cells and silencing of USP9X augments BCL10 ubiquitination and impairs NF-kappaB signaling in T cells."

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IndraLab

Statements

USP9X leads to the deubiquitination of BCL10. 2 / 2

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