IndraLab

Statements


USP9X leads to the deubiquitination of BCL10. 2 / 2
1 | 1

"Mechanistically, USP9X interacts with Bcl10 of the Carma1-Bcl10-Malt1 (CBM) complex and removes the TCR-induced ubiquitin chain from Bcl10, which facilitates the association of Carma1 with Bcl0-Malt1."

reach
"Finally, the ubiquitin specific protease 9X (USP9X) interacts with BCL10 in activated T cells and silencing of USP9X augments BCL10 ubiquitination and impairs NF-kappaB signaling in T cells."