IndraLab

Statements



"The phosphorylation of MAPKs including ERK1/2, p38, and JNK was measured by immunoblot analysis using specific Abs. LPS-induced phosphorylation of ERK1/2, p38, and JNK was inhibited by EGCG (Fig. 4A?C). However, in 67LR-ablated cells, the inhibitory effect of EGCG on LPSinduced upregulation of phosphorylation was attenuated (Fig. 4A?C)."

"Treatment with LPS resulted in significant increases in ERK, JNK, and p38 phosphorylation compared with control, and these events were not inhibited by cotreatment with lutein (Fig. 4D)."

"It is known that LPS stimulation leads to increased activation of three subgroups of MAPKs, i.e., ERK, JNK, and p38, in murine macrophages and human monocytes (38, 39)."

"In addition, activation of JNK and p38 was reduced in lipopolysaccharide (LPS)-stimulated IRAK-4 KD macrophages."