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Phosphorylated STAT1 increases the amount of USP18. 1 / 1

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"In the absence of USP18, signaling through the JAK-STAT pathway should be enhanced with increased levels of phosphorylated STAT1 and STAT2.We used siRNA to knockdown USP18 expression in MDMs and treated them with IFN-for 18 hours and found increased levels of phosphorylated STAT1 and STAT2 (Fig. 4A )."

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IndraLab

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Phosphorylated STAT1 increases the amount of USP18. 1 / 1

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