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OTUB1 inhibits proteolysis. 1 / 1

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"We had previously demonstrated that human Otub1 protein leads to degradation of human GRAIL protein, and in a similar manner, murine Otub1 protein leads to murine GRAIL protein degradation (supplemental Fig. 3).4 Ex vivo isolated naive CD4 T cells express no Otub1 protein, thus allowing GRAIL expression (XREF_FIG, first lane), despite the presence of detectable Otub1 mRNA as mTOR mediated protein translation is inactive in these cells."

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OTUB1 inhibits proteolysis. 1 / 1

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