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"In addition, USP21 knockdown in PC12 cells inhibits nerve growth factor induced neurite outgrowth suggesting its role associated with microtubules XREF_BIBR."

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"Our functional studies indicate a key role for USP21 in the governance of microtubule- and centrosome associated physiological processes : Depletion of USP21 in A549 cells compromises the reestablishment of a radial array of microtubules during recovery from cold induced depolymerization and also reduces the probability of primary cilium formation, whereas USP21 knockdown in PC12 cells inhibits nerve growth factor induced neurite outgrowth."