IndraLab

Statements

EHMT2 methylates TP53 on K373. 6 / 6
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sparser
"Interestingly, EHMT2 methylates lysine 373 in p53 ( xref )."
26763252
sparser
"In addition, G9a methylates p53 at K373 and regulates apoptosis by preserving p53 in an inactive form ( xref )."
30535125
sparser
"Recently, Huang and colleagues have reported that, in addition to acetylation and ubiquitylation, K373 of p53 can also be methylated by two homologous histone methyl- transferases, G9a and Glp [ xref ]."
24298606
sparser
"G9a and GLP methylate p53 at lysine 373 ( xref )."
27580749
sparser
"Other study provides evidence that the G9a-GLP complex methylates p53 protein on Lys 373 residue and inactivates the growth suppression function of p53 in breast and lung cancer cells [ xref ]."
25027955
sparser
"G9a specifically methylates p53 at lysine 373, resulting in its inactivation xref ."
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