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"https://doi.org/10.1101/751578 doi : bioRxiv preprint 312 In our previous work , we described amino acid substitutions in the Ub-binding site of MERS-CoV 313 PL pro that specifically disrupt its DUB activity without affecting the overall proteolytic activity ( 65 ) wt rMERS-CoV on both cell lines ( Fig 1 ) ."
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