Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ZUP1 inhibits proteotoxic ER stress. 1 / 1

| 1

➶

eidos

"DUB inhibition and GSH depletion induces both proteotoxic and ER stress Since DUBs remove ubiquitin groups from proteins , and an accumulation of ubiquitinated proteins can lead to cell death ( D'Arcy and Linder , 2014 ) , we measured total protein ubiquitination in cells eight hours after single agent or combined treatment with BSO and each of the three DUB inhibitors ."

30799286

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...