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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ATXN3 increases the amount of HSPA. 2 / 2

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"The preliminary observation that hsp70 protein appeared to be lower in Atxn3 KO fibroblasts raised the question : does Atxn3 modulate hsp70 levels and if so, is it a sufficiently robust effect to detect in mouse tissue?"

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"Data in the current study are consistent with Atxn3 modulating levels of hsp70 and previous studies are consistent with Atx3 regulating protein degradation suggesting that Atxn3 helps regulate two key cellular processes that protect cells against aberrant proteins."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...