IndraLab

Statements


ATXN3 increases the amount of HSPA. 2 / 2
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"The preliminary observation that hsp70 protein appeared to be lower in Atxn3 KO fibroblasts raised the question : does Atxn3 modulate hsp70 levels and if so, is it a sufficiently robust effect to detect in mouse tissue?"

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"Data in the current study are consistent with Atxn3 modulating levels of hsp70 and previous studies are consistent with Atx3 regulating protein degradation suggesting that Atxn3 helps regulate two key cellular processes that protect cells against aberrant proteins."