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UCHL5 binds SMURF2. 2 / 2

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"UCHL5 binds to Smad7 and deubiquitinates the Smad7-Smurf1/Smurf2 (E3 ubiquitin ligase)-polyubiquitinated TGF-βR1 complex [4,10] ."

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"The deubiquitinating enzyme UCH37/UCHL5 interacts with Smad7 and counteracts the Smurf2-induced ubiquitination of TGF-β type I receptor [ 53 ]."

17317136

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UCHL5 binds SMURF2. 2 / 2

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