IndraLab

Statements


MAP2K1 phosphorylates MAPK1 on Y187. 34 / 34
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rlimsp
"The dual phosphorylation of Thr-183 and Tyr-185 in ERK2 is catalyzed by MAPK/ERK kinase 1 (MEK1)."

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reach
"MEK1 and MEK2 phosphorylate ERK1 and ERK2 on T183 and Y185 residues within the TPY motif (Crews et al., 1992b; Seger et al., 1992; Zheng & Guan, 1993b)."

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"Mapk1 is phosphorylated by map2k1/mek1 and map2k2/mek2 on thr-185 and tyr-187 in response to external stimuli like insulin or ngf. Both phosphorylations are required for activity."

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sparser
"MEK1 and MEK2 phosphorylate ERK1 and ERK2 on T183 and Y185 residues within the TPY motif ."

reach
"As an example of text being converted into an executable model, consider the sentence " MEK1 phosphorylates ERK2 at threonine 185 and tyrosine 187 "."

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sparser
"We used a mass spectrometry-based analysis of the undigested or tryptically digested protein to establish that MKK1 exclusively phosphorylates His 6 -ERK2 on Thr-183 and Tyr-185 within the activation loop."