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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53-R248W increases the amount of CDKN1A. 1 / 1

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"They demonstrated that p53 R248W knockdown by p53 R248W -specific siRNA induced apoptosis in MDAH087 cells carrying only p53 R248W and increased p21 protein levels and MDM2 promoter activity in p53-null H1299 cells transfected with both wtp53 and mutp53 [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...