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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ZUP1 binds Cdc48p. 2 / 2

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"Cdc48p/p97 can simultaneously bind Ufd2p, a U‐box E3 that catalyzes polyubiquitin chain extension, and one of two factors that can counteract its action: Otu1p, a DUB, and Ufd3p protein, a WD40 repeat protein of unknown function that has been shown to be required for Ub‐dependent proteolysis (Ghislain 1996, Johnson 1995)."

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"Cdc48p/p97 can simultaneously bind Ufd2p, a U-box E3 that catalyzes polyubiquitin chain extension, and one of two factors that can counteract its action: Otu1p, a DUB, and Ufd3p protein, a WD40 repeat protein of unknown function that has been shown to be required for Ub-dependent proteolysis (Ghislain et al., 1996; Johnson et al., 1995) ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...