IndraLab

Statements

OTUD7B activates IRF3-associated cargo receptor SQSTM1. 1 / 1

| 1

eidos

"Mechanistically , OTUD7B interacts with IRF3 , and activates IRF3-associated cargo receptor SQSTM1 / p62 ( sequestosome 1 ) by removing its K63-linked poly-ubiquitin chains at lysine 7 ( K7 ) to enhance SQSTM1 oligomerization ."

35100065

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUD7B activates IRF3-associated cargo receptor SQSTM1. 1 / 1

INDRA sources:

Databases

Reading