IndraLab

Statements


Spautin-1 activates USP10. 4 / 4
| 4

reach
"Spautin-1 targets the activity of two ubiquitin specific peptidases, USP10 and USP13 and causes PI3K complex degradation."

reach
"Spautin-1 reportedly inhibits autophagosomal initiation and maturation by inhibiting deubiquitylases USP10 and USP13, which stabilize the Beclin-1 and VPS34 complex (26)."

reach
"Spautin-1 has been recently reported to prevent autophagy by inhibiting the deubiquitinases USP10 and USP13, which leads to beclin 1 and Vps34 (or PI3KIII) degradation [XREF_BIBR]."

reach
"Spautin-1 reportedly suppresses autophagy by inhibiting the USP10 and USP13 deubiquitinases."