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ZUP1 inhibits Middle East Respiratory Syndrome Coronavirus. 1 / 1

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"Importantly, selective interference of PLpro DUB activity could enable future engineering of replication-competent, DUB-deficient MERS-CoV that could be used to investigate the role of PLpro DUB activity during MERS-CoV infection.Not surprisingly, MERS-CoV PLpro has been identified as a target for small-molecule drug design [159], [165], [166], but the development of MERS-CoV-specific antiviral compounds remains in its early stages."

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ZUP1 inhibits Middle East Respiratory Syndrome Coronavirus. 1 / 1

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